PLxGuard™ is an innovative drug delivery platform that selectively delivers active pharmaceutical ingredients (APIs) to targeted portions of the GI tract.
With PLxGuard, APIs are chemically associated with lipidic excipients, and then released based on a pH-dependent mechanism.
GI: gastrointestinal, NSAIDs: nonsteroidal anti-inflammatory drugs
- Lichtenberger LM, et al. Association of phosphatidylcholine and NSAIDs as a novel strategy to reduce gastrointestinal toxicity. Drugs Today. 2009;45(12):877-890.